Ovulation induction is a term used to describe the use of oral or injectable fertility medications (gonadotropins) to stimulate the ovaries to produce mature eggs. The purpose of ovulation induction is to develop and ovulate one or more eggs in a woman who normally does not ovulate. Based on your diagnosis, your doctor will prescribe the treatment most appropriate for you.

Ovulation induction is indicated if you:

  • Have ovulation problems that have not responded to simpler medications (such as clomiphene citrate).
  • Have unexplained infertility and wish to try ovulation induction in order to increase the number of eggs produced in each cycle. With increased egg production the chance of conception also increases.

To be a candidate for ovulation induction you must have a normal uterine cavity, and at least one normal fallopian tube, and your partner must have a normal sperm count.
In the general population, 20% to 25% of healthy, fertile couples become pregnant each month that they are trying to conceive.1 In our experience, ovulation induction typically produces pregnancy rates of 10% to 20% per cycle, depending on a woman’s age, diagnosis, and duration of infertility. Approximately 15% to 20% of gonadotropin pregnancies will miscarry, similar to the general population.2

1American Society for Reproductive Medicine, Age and Fertility, Fertility in the Aging Female, 2012
2Journal of Human Reproductive Sciences, Publication of Indian Society of Assisted Reproduction, Comparative evaluation of pregnancy outcome in gonadotrophin-clomiphene combination vs clomiphene alone in polycystic ovarian syndrome and unexplained infertility–A prospective clinical trial, May-Aug 2010